Some Results for the Generalized Fourier Transform Associated with the Cherednik-Opdam operator on R

In this paper, using a generalized translation operator, we prove the estimates for the generalized Fourier transform in the space L^p_{\alpha,\beta}(R), on certain classes of functions

Learning through personal connections: Cogenerative dialogues in synchronous virtual spaces

This study describes the role of cogenerative dialogues in a synchronous virtual classroom. Cogenerative dialogues are a way for students and instructors to reflect upon in-class events and work collaboratively during the course to optimize teaching and learning. In the present study, cogen has been found to be a tool for enhancing connections among graduate students in the class leading to a reported increase of motivation and engagement. Cogenerative dialogues were essential in shifting responsibilities so that students took a more active role in their own learning while supporting each other

Some Results of 2π-Periodic Functions by Fourier Sums in the Space L p (2π)

Abstract In this paper, using the Steklov function, we introduce the generalized continuity modulus and define the class of functions W r,k p,ϕ in the space L p . For this class, we prove an analog of the estimates i

Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder

Background: Bipolar affective disorder (BPD) is a severe mood disorder with a prevalence of ∼ 1.5% in the population. The pathogenesis of BPD is poorly understood; however, a strong heritable component has been identified. Previous genome-wide association studies have indicated a region on 6q25, coding for the SYNE1 gene, which increases disease susceptibility. SYNE1 encodes the synaptic nuclear envelope protein-1, nesprin-1. A brain-specific splice variant of SYNE1, CPG2 encoding candidate plasticity gene 2, has been identified. The intronic single-nucleotide polymorphism with the strongest genome-wide significant association in BPD, rs9371601, is present in both SYNE1 and CPG2. / Methods: We screened 937 BPD samples for genetic variation in SYNE1 exons 14–33, which covers the CPG2 region, using high-resolution melt analysis. In addition, we screened two regions of increased transcriptional activity, one of them proposed to be the CPG2 promoter region. / Results and Conclusion: We identified six nonsynonymous and six synonymous variants. We genotyped three rare nonsynonymous variants, rs374866393, rs148346599 and rs200629713, in a total of 1099 BPD samples and 1056 controls. Burden analysis of these rare variants did not show a significant association with BPD. However, nine patients are compound heterozygotes for variants in SYNE1/CPG2, suggesting that rare coding variants may contribute significantly towards the complex genetic architecture underlying BPD. Imputation analysis in our own wholegenome sequencing sample of 99 BPD individuals identified an additional eight risk variants in the CPG2 region of SYNE1

Biplot analysis of strawberry genotypes recommended for the State of Espírito Santo.

Most strawberry genotypes grown commercially in Brazil originate from breeding programs in the United States, and are therefore not adapted to the various soil and climatic conditions found in Brazil. Thus, quantifying the magnitude of genotype x environment (GE) interactions serves as a primary means for increasing average Brazilian strawberry yields, and helps provide specific recommendations for farmers on which genotypes meet high yield and phenotypic stability thresholds. The aim of this study was to use AMMI (additive main effects and multiplicative interaction) and GGE biplot (genotype main effects + genotype x environment interaction) analyses to identify high-yield, stable strawberry genotypes grown at three locations in Espírito Santo for two agricultural years. We evaluated seven strawberry genotypes (Dover, Camino Real, Ventana, Camarosa, Seascape, Diamante, and Aromas) at three locations (Domingos Martins, Iúna, and Muniz Freire) in agricultural years 2006 and 2007, totaling six study environments. Joint analysis of variance was calculated using yield data (t/ha), and AMMI and GGE biplot analysis was conducted following the detection of a significant genotypes x agricultural years x locations (G x A x L) interaction. During the two agricultural years, evaluated locations were allocated to different regions on biplot graphics using both methods, indicating distinctions among them. Based on the results obtained from the two methods used in this study to investigate the G x A x L interaction, we recommend growing the Camarosa genotype for production at the three locations assessed due to the high frequency of favorable alleles, which were expressed in all localities evaluated regardless of the agricultural year

Effects of curcumin in an orthotopic murine bladder tumor model

Cigarette smoking (CS) is the main risk factor for bladder cancer development. There are more than 100 carcinogens present in cigarette smoke. Among the potential mediators of CS-induced alterations is nuclear factor-kappa (NF-κB), which is responsible for the transcription of genes related to cell transformation, tumor promotion, angiogenesis, invasion and metastasis. Curcumin is a polyphenol compound derived from Curcuma longa that suppress cellular transformation, proliferation, invasion, angiogenesis, and metastasis by down regulating NF-κB and its regulated genes. The aim of our study was to assess the effects of curcumin in bladder urothelial carcinoma. We studied the effects of curcumin in vitro and in vivo using the orthotropic syngeneic bladder tumor animal model MB49. Curcumin promotes apoptosis of bladder tumor cells in vitro. In vivo tumors of animals treated with curcumin were significantly smaller as compared to controls. Using immunohistochemistry, we demonstrated a decrease in the expression of Cox-2 by 8% and Cyclin D1 by 13% in the animals treated with curcumin; both genes regulated by NF-κB and related to cell proliferation. In this study, we showed that curcumin acts in bladder urothelial cancer, possibly dowregulating NF-κB-related genes, and could be an option in the treatment of urothelial neoplasms. The results of our study suggest that further research is warranted to confirm our findings

Repeatability and minimum number of evaluations for morpho-agronomic characters of elephant-grass for energy purposes.

ABSTRACT Due to the need to promote information relevant to elephant-grass breeding programs for energy purposes, this work aimed to estimate the coefficient of repeatability of the main morpho-agronomic characters and to predict the minimum number of cuts required for selection with greater efficiency. A total of 73 elephant-grass genotypes were evaluated in a randomized block design, in a subdivided plot scheme with two replicates. Nine cuts were performed at six-month intervals, from June 2012 to December 2016, in the municipality of Campos dos Goytacazes, RJ. We estimated the repeatability coefficients for dry matter yield (DMY), number of tillers (NT), plant height (PH), stem diameter (SD) and leaf blade width (LBW), using the methods of analysis of variance, principal components and structural analysis. At least nine, three, six, six and three cuts should be performed, considering the DMY, NT, PH, SD and LBW characteristics, respectively, to predict the true value of the genotypes with 80% reliability

Caracterização morfologica e agronomica de algumas cultivares de capim-elefante.

bitstream/item/143038/1/2058.pd

Titchmarsh theorems for Fourier transforms of Hölder-Lipschitz functions on compact homogeneous manifolds

There have been changes in leadership in both the Student Activities Board and the Student Government Association. The Associate Dean of Students Sophie Wisniewski provides an update on the review of the Judicial Board in light of issues concerning sexual assault on campus. Letters to the editor respond to changes in financial aid for international students and a previous article about political interactions with Republicans on campus. The Women\u27s Issues Block discusses abortion.https://openworks.wooster.edu/voice1981-1990/1444/thumbnail.jp